Clopidogrel monotherapy versus aspirin monotherapy in patients with established cardiovascular disease: systematic review and meta-analysis

PT Tasoudis, IG Kyriakoulis, D Sagris… - Thrombosis and …, 2022 - thieme-connect.com
aspirin for secondary prevention of cardiovascular disease (class I, level A recommendation),
and clopidogrel as an alternative in case of aspirin … Particularly in patients with high risk

Aspirin for secondary prevention of cardiovascular disease

RA Byrne, R Colleran - The Lancet, 2020 - thelancet.com
… in patients with stable cardiovascular disease. The main strength in comparison with previous
analyses is that the study incorporates evidence not only with clopidogrel … , clopidogrel is …

Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicentre randomised trial

Y Wang, C Johnston, PM Bath, X Meng… - Stroke and vascular …, 2021 - svn.bmj.com
… may not provide additional benefit in stroke prevention compared with aspirin alone for the
… alleles were at higher risk of vascular events than non-carriers when taking clopidogrel.7 …

[HTML][HTML] Aspirin in the modern era of cardiovascular disease prevention

E Murphy, JMG Curneen… - … DeBakey Cardiovascular …, 2021 - ncbi.nlm.nih.gov
… by clopidogrel monotherapy without aspirin, as the treatment of choice for those at very high
risk of … for a select group of primary prevention patients who are at higher risk of CVD but low …

Rivaroxaban plus aspirin for the prevention of ischaemic events in patients with cardiovascular disease: a cost-effectiveness study

S Petersohn, X Pouwels, B Ramaekers… - … cardiology, 2020 - academic.oup.com
aspirin antiplatelet therapy in coronary artery disease, and additionally to clopidogrel antiplatelet
therapy in peripheral arterial diseaseprevention risk score (high score = higher risk of …

Dual antiplatelet therapy with clopidogrel and aspirin versus aspirin monotherapy in patients undergoing coronary artery bypass graft surgery

J Qu, H Zhang, C Rao, S Chen, Y Zhao… - … of the American Heart …, 2021 - Am Heart Assoc
prevent major adverse cardiovascular events. However, patients treated with CABG still have
a notable risk of … There was no evidence of a higher risk of major bleeding among patients

P2Y12 inhibitor versus aspirin monotherapy for secondary prevention of cardiovascular events: meta-analysis of randomized trials

D Aggarwal, K Bhatia, ZS Chunawala… - European heart …, 2022 - academic.oup.com
… was reported as low risk, some concern, or high risk. … aspirin with clopidogrel while 4
studies compared aspirin with ticagrelor. Six trials enrolled patients with coronary artery disease

Secondary prevention of antithrombotic therapy in patients with stable cardiovascular disease at high ischemic risk: a network meta-analysis of randomized controlled …

H Zhu, X Xu, H Wang, Q Chen, X Fang… - … in Cardiovascular …, 2023 - frontiersin.org
… of major bleeding to varying degrees, with ticagrelor plus aspirin associated with the highest
risk of major bleeding. The net clinical benefit favored clopidogrel or ticagrelor monotherapy…

P2Y12 inhibitors plus aspirin versus aspirin alone in patients with minor stroke or high-risk transient ischemic attack

ZX Li, Y Xiong, HQ Gu, M Fisher, Y Xian, SC Johnston… - Stroke, 2021 - Am Heart Assoc
… than aspirin alone for recurrent stroke prevention with a … search for aspirin plus clopidogrel
or aspirin plus ticagrelor … of stroke, MI, or cardiovascular disease (CVD) death.A, Myocardial …

Efficacy and safety of rivaroxaban plus clopidogrel versus aspirin plus clopidogrel in patients with coronary atherosclerotic heart disease and gastrointestinal disease …

T Zhou, Y Gong, J Li, Y Wang, X Wang - Trials, 2023 - Springer
… as clopidogrel, also have an increased risk of GIB, but by a different mechanism from aspirin,
increasing the risk … a new strategy for the secondary prevention of CHD combined with GID …